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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6194390 B1

PDFFull Text
Date of Patent:
Feb. 27, 2001

Filed:

Feb. 03, 2000

Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis

Applicant:
Inventors:

Franco Lori, Parma, IT;

Andrea Cara, Rockville, MD (US);

Wen-Yi Gao, Rockville, MD (US);

Robert C. Gallo, Bethesda, MD (US);

Assignee:

The United States of America as represented by the Department of Health and Human Services, Washington, DC (US);

Attorney:

Knobbe, Martens Olson & Bear, LLP

Primary Examiner:

Gary Geist

Assistant Examiner:

L E Crane

Int. Cl.
CPC ...
A61K 3/170 ;
U.S. Cl.
CPC ...
A61K 3/170 ;
Abstract

A method for inhibiting replication of reverse transcriptase dependent virus in plant or animal cells, comprising the step of administering to said cells a compound that depletes the intracellular pool of deoxyribonucleoside phosphate in an amount effective to inhibit replication of said virus. Hydroxyurea is one such suitable compound. Also disclosed is a method for producing incomplete reverse-transcriptase dependent viral DNA, by administering a deoxyribonucleoside phosphate-depleting drug to cells infected with such a virus.

Find Patent Forward Citations

Lori, Franco. (2001). Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis (U.S. Patent No. 6194390). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6194390

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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