The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2001
Filed:
Oct. 19, 1998
Applicant:
Inventors:
Kohei Miyazono, Shiki, JP;
Hidenori Ichijo, Bunkyo-ku, JP;
Assignee:
Japanese Foundation for Cancer Research, Tokyo-to, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/12 ; C12N 1/20 ; C12N 1/500 ; A61K 3/851 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 9/12 ; C12N 1/20 ; C12N 1/500 ; A61K 3/851 ; C07H 2/104 ;
Abstract
An object of the present invention is to provide a protein which induces apoptosis, a base sequence encoding the protein, and an agent for use in the treatment of malignant tumors. The present invention is a protein (ASK1) which has protein kinase activity and enhances SEK1 kinase activity and/or MKK3 kinase activity, or a derivative thereof. Malignant tumors can be treated using the protein according to the present invention or the base sequence encoding the protein.