The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2001
Filed:
Sep. 03, 1998
Applicant:
Inventors:
Monica Marija Palcic, Edmonton, CA;
Keiko Sujino, Edmonton, CA;
Assignee:
Synsorb Biotech Inc., Calgary, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/918 ;
U.S. Cl.
CPC ...
C12P 1/918 ;
Abstract
Disclosed are methods for the enzymatic synthesis of &agr;-sialylated oligosaccharide glycosides. Specifically, in the disclosed methods, &agr;2,3-sialyltransferase is used to transfer an analogue of sialic acid, employed as its CMP-nucleotide derivative, to the non-reducing sugar terminus of an oligosaccharide having a fucosyl group in the penultimate saccharide unit to the non-reducing sugar terminus. The analogue of sialic acid and the oligosacchairde employed in this method are selected to be compatible with the sialyltransferase employed.