The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2001
Filed:
Feb. 06, 1998
Olympus Optical Co., Ltd., Tokyo, JP;
Abstract
A method for detecting a target nucleic acid molecule hybridized with a nucleic acid probe, comprising the steps of: (a) hybridizing a target nucleic acid molecule having a specific sequence to be detected in a sample with a nucleic acid probe having a sequence complementary to the sequence of the nucleic acid molecule, the nucleic acid probe being selected such that the nucleic acid molecule and the probe are partially hybridized to represent a linear conformation in a hybridized region and to represent, in an non-hybridized region, a unique structure inherent to its nucleotide sequence; (b) measuring the conformation, structure and length of the nucleic acid molecule obtained in step (a); and (c) on the basis of the measurement data obtained in the step (b), detecting the nucleic acid containing both of the linear conformation and the unique structure, thereby detecting the nucleic acid molecule hybridized with the probe.