The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 27, 2001

Filed:

Sep. 17, 1997
Applicant:
Inventors:

Stacey Efstathiou, Cambridge, GB;

Robin H. Lachmann, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ; C12N 1/500 ; C12N 1/12 ;
U.S. Cl.
CPC ...
A61K 3/912 ; C12N 1/500 ; C12N 1/12 ;
Abstract

Constructs for the delivery of sequences of interest to cells include a herpes virus latency active promoter (LAP) of the latency associated transcript (LAT) region. An internal ribosome entry site (IRES) is located downstream of the LAP, with a nucleotide sequence of interest downstream of the IRES. Stable, long-term expression including export of mRNA to the cytoplasm and translation of the encoded polypeptide, is found in neuronal and non-neuronal cells.


Find Patent Forward Citations

Efstathiou, Stacey. (2001). Replication defective herpes simplex virus comprising heterologous inserts (U.S. Patent No. 6193980). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6193980

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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