The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2001

Filed:

Mar. 20, 1996
Applicant:
Inventors:

Guy T. Mullenbach, San Francisco, CA (US);

Jeffrey M. Blaney, Oakland, CA (US);

Steven Rosenberg, Oakland, CA (US);

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/518 ; C07K 1/4485 ; A61K 3/818 ;
U.S. Cl.
CPC ...
C12N 1/518 ; C07K 1/4485 ; A61K 3/818 ;
Abstract

EGF muteins in which the histidine at position 16 is replaced with a neutral or acidic amino acid exhibit activity at pHs lower than obtainable with wild type EGF.


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