The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2001
Filed:
Apr. 17, 1995
Applicant:
Inventors:
J. Robert Putnak, Silver Spring, MD (US);
Kenneth Eckels, Rockville, MD (US);
Doria R. Dubois, Wheaton, MD (US);
Kevin Cassidy, Toronto, CA;
Assignee:
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/912 ; C07K 1/418 ; C12N 7/04 ;
U.S. Cl.
CPC ...
A61K 3/912 ; C07K 1/418 ; C12N 7/04 ;
Abstract
An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models. Uses of the inactivated dengue virus for detecting antibodies to dengue and kits therefor are also described.