The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2001
Filed:
Nov. 12, 1998
Akira Mizuno, Kyoto, JP;
Makoto Shibata, Ashikaga, JP;
Tomoe Kamei, Takatsuki, JP;
Norio Inomata, Mino, JP;
Suntory Limited, Osaka, JP;
Abstract
Disclosed are pyrroloazepine compounds and their salts. These pyrroloazepine compounds are represented by formula (I) wherein the dashed line indicates the presence or absence of a bond; and, when the bond is present, Z,is not present and Z,is H but, when the bond is absent, Z,and Z,are both Hs; Z,is H and Z,is OH; Z,and Z,are both SR,s in which R,is alkyl, aralkyl or aryl; or Z,and Z,are combined together to represent O, NOR,in which R,is H, alkyl, aralkyl or aryl, or C,-C,alkylenedithio; R is H, alkyl, cycloalkyl, cycloalkyl alkyl or aralkyl; and the ring P is a specific pyrrole ring. These pyrroloazepine compounds and salts are effective as preventives or therapeutics for general circulatory diseases such as hypertension, heart failure, ischemic hear diseases, cerebrovascular disturbances and peripheral circulatory disturbances. Their production processes are also disclosed