The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2001

Filed:

Mar. 16, 1999
Applicant:
Inventors:

Jiri J Krepinsky, Newmarket, Ontario, CA;

Jacek Chociej, late of Toronto, CA;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/368 ; G01N 3/353 ; C12Q 1/26 ;
U.S. Cl.
CPC ...
G01N 3/368 ; G01N 3/353 ; C12Q 1/26 ;
Abstract

A method for detecting neoplasia or cancer of the colon or rectum comprising obtaining a sample of colorectal mucus from the rectum of a patient, and detecting the presence of a marker selected from the group consisting of long chain aliphatic aldehydes containing 12-20 carbon atoms, particularly CH,(CH,),CHO and CH,(CH,),CHO; and plasmalogen-bound precursors thereof. Preferably the method comprises treating the sample with Schiff's Reagent and detecting neoplasia or cancer of the colon or rectum based upon the coloration produced at about 560-590 nm in the sample by the treatment. The method does not require the step of adding an enzyme for detecting the disaccharide marker &bgr;-D-Gal(1-3)-D-GalNAc(&agr;1-Thr/Ser) and a saccharide marker containing D-galactose and/or 2-acetamido-2-deoxy-D-galactose.


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