The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 13, 2001
Filed:
Feb. 03, 1998
Applicant:
Inventor:
Arthur J. Sytkowski, Arlington, MA (US);
Assignee:
Beth Israel Deaconess Medical Center, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/562 ; C12N 1/518 ; C07K 1/4505 ; A61K 3/818 ;
U.S. Cl.
CPC ...
C12N 1/562 ; C12N 1/518 ; C07K 1/4505 ; A61K 3/818 ;
Abstract
Provided are nucleic acids encoding multimeric erythropoietin (EPO) proteins and having modifications in the 5′ and 3′ noncoding sequences relative to the corresponding sequences in native EPO DNA. The invention also relates to the use of such nucleic acids to produce multimeric EPO proteins, which may have altered activity as compared to EPO multimers expressed from nucleic acids having native 5′ and 3′ sequences.