The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2001

Filed:

Jan. 28, 1999
Applicant:
Inventors:

Yu-Chang John Wang, Newport Beach, CA (US);

Bing Yang, Redwood City, CA (US);

Robert N. Jennings, Jr., San Jose, CA (US);

Andrew A. Protter, Palo Alto, CA (US);

Assignee:

Scios Inc., Sunnyvale, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/02 ; A61K 4/730 ; A61K 4/732 ;
U.S. Cl.
CPC ...
A61F 2/02 ; A61K 4/730 ; A61K 4/732 ;
Abstract

Compositions and devices for the controlled release delivery of a peptide or protein drug are produced by dispersing a glassy matrix phase comprising the peptide or protein drug and a thermoprotectant in a bioerodable, biocompatible polymer at a temperature that is below the glass transition temperature of the glassy matrix phase and above the melting point of the polymer. The method and composition of the invention may be employed for the local delivery of angiogenic amounts of basic fibroblast growth factor or vascular endothelial growth factor.


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