The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2001

Filed:

Mar. 01, 1999
Applicant:
Inventors:

Sumedha Jayasena, Boulder, CO (US);

Larry Gold, Boulder, CO (US);

Assignee:

NeXstar Pharmaceuticals, Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/934 ; C07H 2/102 ; C07H 2/104 ; C12N 9/12 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/934 ; C07H 2/102 ; C07H 2/104 ; C12N 9/12 ;
Abstract

This invention discloses high-affinity oligonucleotide ligands to the thermostable Taq polymerase, Tth polymerase and TZ05 polymerase. Specifically, this invention discloses DNA ligands having the ability to bind to the Taq, Tth and TZ05 polymerases and the methods for obtaining such ligands. The ligands are capable of inhibiting polymerases at any predetermined temperature.


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