The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2001
Filed:
Mar. 22, 1999
Applicant:
Inventors:
Aomar Ouali, Boisbriand, CA;
Abul Kalam Azad, Montreal, CA;
Assignee:
Pharmascience Inc., Montreal, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/22 ; A61K 9/24 ; A61K 9/52 ; A61K 9/54 ;
U.S. Cl.
CPC ...
A61K 9/22 ; A61K 9/24 ; A61K 9/52 ; A61K 9/54 ;
Abstract
A pharmaceutical composition is provided for the oral administration of an NSAID and a prostaglandin. The composition is a solid dosage form wherein the NSAID is enterically coated and the prostaglandin is present along with an effective stabilizing amount of a prostaglandin stabilizing agent such as hydroxypropyl methylcellulose or polyvinylpyrrolidone. Exemplary dosage forms are bilayer tablets in which the prostaglandin is misoprostol and the NSAID is diclofenac, piroxicam, or a pharmaceutically acceptable salt thereof. Methods for using the composition to treat NSAID-responsive conditions, disorders and diseases are provided as well.