logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6180769 B1

PDFFull Text
Date of Patent:
Jan. 30, 2001

Filed:

Nov. 12, 1997

Method for linking negatively charged macrobiomolecules to plastics, resulting linked compositions and microtitre plates incorporating same

Applicant:
Inventors:

Antonius Henricus Minardus Severus Marie Van Kuppevelt, Nijmegen, NL;

Christiaan Hendrikus Adriaan Van de Lest, Zeist, NL;

Jacobus Henricus Veerkamp, Nijmegen, NL;

Assignee:

Angiomed GmbH & Co. Medizentechnik KG, Karlsruhe, DE;

Attorney:

Darby & Darby

Primary Examiner:

Scott W Houtteman

Int. Cl.
CPC ...
C07H 2/104 ;
U.S. Cl.
CPC ...
C07H 2/104 ;
Abstract

A method for linking strongly negatively charged biological macromolecules like deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and glycosaminoglycans (GAG) to plastic substrates, comprising contacting the macromolecules and the plastics with a non chaotropic solution containing a salt in an amount of at least 20% of its saturation concentration, or having a pH below the pKa of the charged groups of the macromolecules to be linked. Also disclosed are the products of the method, in particular a microtiter plate with plastic wells coated with the negatively charged non-proteinaceous macrobiomolecules.

Find Patent Forward Citations

Van Kuppevelt, Antonius Henricus Minardus Severus Marie. (2001). Method for linking negatively charged macrobiomolecules to plastics, resulting linked compositions and microtitre plates incorporating same (U.S. Patent No. 6180769). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6180769

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…