The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2001
Filed:
Apr. 12, 1995
Applicant:
Inventors:
G{umlaut over (u)}nter Wich, M{umlaut over (u)}nchen, DE;
Walfred Leinfelder, M{umlaut over (u)}nchen, DE;
Keith Backman, Bedford, MA (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/322 ; C12N 1/20 ; C12N 1/21 ; C12N 1/500 ;
U.S. Cl.
CPC ...
C12P 1/322 ; C12N 1/20 ; C12N 1/21 ; C12N 1/500 ;
Abstract
A tryptophan producing strain of microorganism is selected from,and Corynebacteria and is tryptophan feedback resistant and serine feedback resistant. The serine feedback resistance is by a mutation in a serA allele, where the mutated serA allele codes for a protein which has a K,value for serine between 0.1 mM and 50 mM. The tryptophan feedback resistance is by a trpE allele which codes for a protein which has a K,value for tryptophan between 0.1 mM and 20 mM. A process for preparing this microorganism and a process for using this microorganism are disclosed.