The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2001
Filed:
May. 19, 1998
Applicant:
Inventors:
Daniel C. Stein, Silver Spring, MD (US);
Charles K. Stover, Mercer Island, WA (US);
Assignee:
University of Maryland, College Park, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9095 ;
U.S. Cl.
CPC ...
A61K 3/9095 ;
Abstract
The invention relates to a hyperblebbing strain of,which produces large amounts of blebs useful for production of blebosomes containing antigens for use as a vaccine delivery vehicle or as a diagnostic reagent. The invention also relates to a method for producing high levels of a desired protein in purified form using the hyperblebbing strain of,, and to a vaccine delivery systems containing the blebosomes expressing the desired antigen.