The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2001
Filed:
Apr. 30, 1999
Applicant:
Inventors:
Johannes Maria F. G. Aerts, Abcoude, NL;
Upendra Kumar Pandit, Amsterdam, NL;
Gerrit-Jan Koomen, Heiloo, NL;
Herman Steven Overkleeft, Leiden, NL;
Paola Vianello, San Bovio, IT;
Assignee:
Universiteit van Amsterdam, , NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/1445 ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/1445 ;
Abstract
Deoxynojirimycin derivatives containing a large hydrophobic moiety, such as cholesterol or adamantame-methanol, linked through a spacer, such as pentamethylene, to the nitrogen atom of deoxynojirimycin, and salts thereof, inhibit glucosylceramidase and may be useful in the treatment of diseases involving a ceramide-mediated signaling process, such as Gaucher disease.