The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2001

Filed:

Jun. 29, 1998
Applicant:
Inventor:

Angel F Lopez, Adelaide, AU;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/900 ; A61K 3/9395 ; A61K 3/944 ; C07K 1/628 ;
U.S. Cl.
CPC ...
A61K 3/900 ; A61K 3/9395 ; A61K 3/944 ; C07K 1/628 ;
Abstract

Anti IL-3 Receptor alpha chain monoclonal antibody (MoAb) is the product of a hybridoma cell line designated 7G3. The MoAb acts as an antagonist to IL-3 in vitro activity. The MoAb binds to the N terminal domain of the IL-3 receptor alpha chain and does so competitively with IL-3 which indicates that this is, at least in part, involved in IL-3 binding. Treatment with the MoAb or fragment thereof, whether recombinant or otherwise, may be suitable for the treatment of one or more of the following conditions: myeloid leukemias, lymphomas such as follicular B cell lymphoma, or the alleviation of allergies.


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