The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2001
Filed:
Mar. 20, 1998
Applicant:
Inventors:
Howard Marcellus Johnson, Gainesville, FL (US);
Carol Hanlon Pontzer, Silver Spring, MD (US);
Assignee:
University of Florida, Gainesville, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/4555 ; A61K 3/821 ; C12N 1/520 ;
U.S. Cl.
CPC ...
C07K 1/4555 ; A61K 3/821 ; C12N 1/520 ;
Abstract
The invention provides fusion proteins comprising an N-terminal region derived from an interferon-tau (IFN-&tgr;) polypeptide and a C-terminal region derived from another type I interferon polypeptide, such as IFN-&agr; or IFN-&bgr;. The fusion proteins exhibit reduced cytotoxicity as compared to the corresponding unmodified type I interferons.