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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6174722 B1

PDFFull Text
Date of Patent:
Jan. 16, 2001

Filed:

Mar. 11, 1998

In-vitro transcription processes for screening natural products and other chemical substances

Applicant:
Inventors:

Bernd Kirschbaum, Mainz, DE;

Wilhelm Stahl, Idstein, DE;

Irvin Winkler, Liederbach, DE;

Michael Meisterernst, Eichenau, DE;

Assignee:

Aventis Pharma Deutschland GmbH, , DE;

Attorney:

Foley & Lardner

Primary Examiner:

Kenneth R Horlick

Assistant Examiner:

Jeffrey Siew

Int. Cl.
CPC ...
C12N 1/563 ; C12N 1/564 ; C12Q 1/68 ; G01N 3/353 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/563 ; C12N 1/564 ; C12Q 1/68 ; G01N 3/353 ; C07H 2/104 ;
Abstract

An process for analyzing transcription which can be automated and which is suitable for bulk screening. The process involves transcribing a DNA sequence using a nuclear extract, which can be complemented or fully replaced by exogenous transcription factors and/or cofactors; optionally removing the proteins of the reaction mixture; binding the resulting transcript to a solid matrix; removing the excess labeled nucleotides; and determining the amount of labeled transcript. Methods of using the inventive process to identify compounds having a selective effect on gene expression.

Find Patent Forward Citations

Kirschbaum, Bernd. (2001). In-vitro transcription processes for screening natural products and other chemical substances (U.S. Patent No. 6174722). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6174722

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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