The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2001

Filed:

Apr. 27, 1999
Applicant:
Inventors:

Michael M. Chartrain, Westfield, NJ (US);

Norihiro Ikemoto, Edison, NJ (US);

Anthony O. King, Somerville, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/22 ; C07C 1/04 ;
U.S. Cl.
CPC ...
C12P 7/22 ; C07C 1/04 ;
Abstract

A process for preparing cis-(1S,2R)-indanediol is disclosed. The process comprises (A) fermenting a culture medium containing a yeast strain selected from the group consisting of,MY 1506 (ATCC 74440) and mutants thereof and 1,2-indanedione to form cis-(1S,2R)-indanediol; and (B) recovering cis-(1S,2R)-indanediol from the culture medium. A process for preparing (1S)-amino-(2R)-indanol from the recovered cis-(1S,2R)-indanediol via the Ritter reaction is also disclosed.


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