The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2001
Filed:
May. 14, 1999
Applicant:
Inventors:
Joseph D. Levine, Louisville, CO (US);
Izydor A. Apostol, Boulder, CO (US);
Assignee:
Baxter Biotech Technology Sarl, Neuchatel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C07K 1/4805 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C07K 1/4805 ;
Abstract
The present invention relates to methods of controlling beta dimer formation in hemoglobin solutions by altering the metal binding site adjacent to the N-terminus of beta globins. The invention further relates to methods of producing stable, intramolecularly crosslinked beta globins by exposure to Ni(II) and oxone.