The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2001

Filed:

Jun. 14, 1999
Applicant:
Inventors:

Robert G. Korneluk, Ottawa, CA;

Martin Holcik, Ottawa, CA;

Peter Liston, Ottawa, CA;

Assignee:

Apoptogen, Inc., Ottawa, CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 2/106 ; C12P 1/934 ; C12Q 1/68 ; C12N 1/500 ; A61K 4/800 ;
U.S. Cl.
CPC ...
C12P 2/106 ; C12P 1/934 ; C12Q 1/68 ; C12N 1/500 ; A61K 4/800 ;
Abstract

The invention features purified nucleic acid encoding a novel internal ribosome entry site (IRES) sequence from the X-linked inhibitor of apoptosis (XIAP) gene. The invention also features methods for using the XIAP IRES to increase cap-independent translation of polypeptide coding sequences linked to the XIAP IRES, and methods for isolating compounds that modulate cap-independent translation.


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