The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2001
Filed:
Nov. 03, 1995
Applicant:
Inventors:
Peter C. Meltzer, Lexington, MA (US);
Bertha K. Madras, Newton, MA (US);
Alan Davison, West Roxbury, MA (US);
Paul Blundell, Somerville, MA (US);
Ashfaq Mahmood, Brookline, MA (US);
Alun G. Jones, Newton Centre, MA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 5/100 ; A61M 3/614 ;
U.S. Cl.
CPC ...
A61K 5/100 ; A61M 3/614 ;
Abstract
Radiopharmaceutical compounds are disclosed. A tropane compound is linked through the N atom at the 8-position to a chelating ligand capable of complexing technetium or rhenium to produce a neutral labeled complex that selectively binds to the dopamine transporter. These compounds can be prepared as separate diastereoisomers as well as a mixture of diastereoisomers. Also disclosed are radiopharmaceutical kits for preparing the labeled radiopharmaceutical compounds.