The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2001

Filed:

Nov. 07, 1997
Applicant:
Inventors:

Yukio Sato, Tokyo, JP;

Hiroaki Kitaoka, Tokyo, JP;

Tatsuya Terada, Tokyo, JP;

Makoto Ono, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/140 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/140 ; C07D / ;
Abstract

An anhydrous crystal of a compound represented by the formula: R,—CH,CONH—R,wherein R,represents a substituted or non-substituted pyridyl group or substituted or non-substituted phenyl group and R,represents a substituted or non-substituted 2-oxo-1-pyrrolidinyl group, characterized in that said crystal is substantially free from hygroscopicity. For example, by drying a hydrous crystal of said compound at a temperature of 80° C. or above under reduced pressure, an anhydrous crystal is provided that exhibits a weight increase of 1% or less when stored under the relative humidity of 83% at the temperature of 25° C. for 30 days. By using the anhydrous crystal for the manufacture of a medicament comprising the compound as an active ingredient, a product with a constant content of the active ingredient can be obtained.


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