The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2000
Filed:
Jul. 08, 1998
Applicant:
Inventors:
Torben Vedel Borchert, Jyllinge, DK;
Stanislas Dusko Ehrlich, Paris, FR;
Assignee:
Novo Nordisk A/S Novo Alle, Bagsvaerd, DK;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435-6 ; 435 691 ; 435471 ; 435476 ; 435488 ; 4353201 ; 435489 ; 43525233 ; 435189 ; 435193 ; 435195 ;
Abstract
A method for in vivo production of a library in cells comprising a multitude of mutated genetic elements, wherein an error-prone polymerase is used in each ancestral cell to replicate all or a part of a genetic element independently of the host chromosomal replication machinery. The genetic element comprises