The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2000
Filed:
Jul. 01, 1998
Robert L Garcea, Boulder, CO (US);
JoAnn A Suzich, Washington Grove, MD (US);
Michael P McCarthy, Poolesville, MD (US);
Robert C Rose, Dansville, NY (US);
University of Colorado, University Technology Corporation, Boulder, CO (US);
MedImmune, Inc., Gaithersburg, MD (US);
University of Rochester, Office of Research and Project Administration, , US;
Abstract
The present invention relates to stable HPV capsomeres which express at least one virus-neutralizing conformational epitope of a native HPV L1 protein which are substantially incapable of assembly into virus-like particles. These capsomeres, because of their smaller size, and immunogenic properties are well suited for use in HPV vaccines and as diagnostic agents. Moreover, because of their smaller size (relative to VLPs), these stable capsomeres may be easily purified and should result in HPV vaccines of enhanced homogeneity.