The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2000

Filed:

Oct. 21, 1999
Applicant:
Inventors:

Raja R Mamidi, Pomona, CA (US);

Andranik Bagdasarian, San Dimas, CA (US);

Gorgonio Canaveral, Walnut, CA (US);

Kazuo Takechi, Osaka, JP;

Assignee:

Alpha Therapeutic Corporation, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
5303901 ; 530386 ; 5303871 ; 53038825 ; 5303891 ; 5303905 ; 530402 ; 530416 ; 530418 ; 530427 ; 424 855 ; 4241301 ; 435236 ; 435238 ; 435239 ; 514-2 ; 514-8 ; 514 21 ;
Abstract

A process for producing an intravenously-administrable gamma globulin solution substantially free of contaminating viruses by heat treating for viral inactivation and fractionating an impure gamma globulin solution and then treating the purified gamma globulin with a solvent-detergent for further viral inactivation. In a continuous process disclosed herein, partially purified gamma globulin solids is not recovered as an intermediate product during the disclosed process. In the continuous process, the fractionation to obtain a purified gamma globulin solution is carried out without precipitation of the desired gamma globulin.


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