The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2000

Filed:

Mar. 12, 1997
Applicant:
Inventors:

Thomas Dale Penning, Emhurst, IL (US);

Stella Siu-tzyy Yu, Morton Grove, IL (US);

James Malecha, Libertyville, IL (US);

Chi-Dean Liang, Glenview, IL (US);

Mark Andrew Russell, Gurnee, IL (US);

Assignee:

G.D. Searle & Co., Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
514438 ; 514444 ; 514445 ; 514447 ; 514604 ; 514605 ; 514365 ; 514369 ; 514370 ; 514342 ; 514255 ; 549 59 ; 549 68 ; 549 77 ; 564 91 ; 564 99 ; 548187 ; 548195 ; 548198 ; 548204 ; 5462804 ;
Abstract

The present invention provides compounds having the of the formula I: ##STR1## and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB.sub.4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.


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