The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2000

Filed:

Jan. 22, 1998
Applicant:
Inventors:

Junko Kudo, Ibaraki, JP;

Motoo Hazama, Toyonaka, JP;

Norihiko Hirata, Suita, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ;
U.S. Cl.
CPC ...
435121 ;
Abstract

There is provided a process for producing N-substituted azetidine-.2-carboxylic acid of the formula I: ##STR1## wherein R.sup.1 denotes an aralkyl group or an arylated lower alkoxycarbonyl group and * designates an asymmetric carbon atom, which is characterized by: reacting an N-substituted azetidine-2-carboxylic acid ester of the formula II: ##STR2## wherein R.sup.1 has the same meaning as defined above and R.sup.2 denotes an alkyl group, an aralkyl group or an allyl group, with an enzyme capable of selectively hydrolyzing a stereoisomer based on the carbon atom of the 2-position of the azetidine ring.


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