The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 19, 2000

Filed:

Sep. 11, 1998
Applicant:
Inventors:

Irena Bronstein, Newton, MA (US);

Brooks Edwards, Cambridge, MA (US);

John Voyta, Sudbury, MA (US);

Rouh-Rong Juo, Allston, MA (US);

Assignee:

Tropix, Inc., Bedford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; C07D / ; C07D / ; C07D / ; C12N / ;
U.S. Cl.
CPC ...
435-792 ; 435-6 ; 435 28 ; 435188 ; 435968 ; 546102 ; 546104 ; 549 24 ; 549223 ; 549225 ;
Abstract

Xanthan esters and acridans are substrates for horseradish peroxidase. These stable, enzymatically cleavable chemiluminescent esters are substrates for horseradish peroxidase which, together with peroxide is among the extensively used enzyme in enzyme-linked detection methods, including immunoassays, oligonucleotide detection and nucleic acid hybridization. The novel compounds are used, together with peroxide, alkali and the peroxidase, to indicate the presence and/or concentration of target compounds. The assays may be enhanced by the use of polymeric quaternary onium enhancement compounds or similar compounds selected to enhance the chemiluminescence emitted.


Find Patent Forward Citations

Loading…