The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2000
Filed:
Jun. 17, 1998
Bharat Lagu, Maywood, NJ (US);
TG. Murali Dhar, Newark, DE (US);
Dhanapalan Nagarathnam, Ramsey, NJ (US);
Yoon T Jeon, Ridgewood, NJ (US);
Mohammad R Marzabadi, Ridgewood, NJ (US);
Wai C Wong, Livingston, NJ (US);
Charles Gluchowski, Danville, CA (US);
Synaptic Pharmaceutical Corporation, Paramus, NJ (US);
Abstract
This invention is directed to oxazolidinone compounds which are selective antagonists for human .alpha..sub.1A receptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia and for the treatment of any disease where the antagonism of the .alpha..sub.1A receptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.