The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2000
Filed:
Aug. 18, 1999
Applicant:
Inventors:
Susan Jane Berners-Price, Paddington, AU;
Richard John Bowen, Cleveland, AU;
Peter Gordon Parsons, St. Lucia, AU;
Assignee:
Griffith University, Queensland, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514 89 ; 428601 ; 428608 ;
Abstract
A method of treatment or inhibition of tumors involves administering a compound to a subject. The compound is one in which one or more of the eight phenyl substituents in the compound [M(dppe).sub.2 ].sup.+, in which M is selected from Au(I), Ag(I) and Cu(I), is substituted by 2, 3, or 4 pyridyl substituents. The compound has anti-tumor activity and an octanol/water partition coefficient between 0.01 and 25.5. The compound has selective toxicity to cancer cells, including cisplatin resistant human carcinoma cells lines.