The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2000
Filed:
May. 20, 1997
Applicant:
Inventors:
Albert C Gyorkos, Westminster, CO (US);
Lyle W Spruce, Arvada, CO (US);
Axel H Leimer, Lakewood, CO (US);
John C Cheronis, Conifer, CO (US);
Assignee:
Cortech, Inc., , US;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 17 ; 435-11 ; 514 18 ; 514 19 ; 514 20 ; 514361 ; 514362 ; 514363 ; 514364 ; 514383 ; 530330 ; 530331 ; 530332 ; 548128 ; 548131 ; 548136 ; 548143 ; 5482668 ; 5482682 ;
Abstract
Provided are methods of inhibiting the activity of a serine protease using protease inhibitors that include an alpha-keto heterocycle in their structure. The methods are useful in the treatment of ischemic heart or treatment of symptoms associated with blood coagulation disorders. Also provided are methods for detecting or quantifying the activity of a serine protease in a pure sample.