The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2000
Filed:
Jan. 30, 1998
Keith W Kardos, Bethlehem, PA (US);
R Sam Niedbala, Allentown, PA (US);
Jarrett Lee Burton, Allentown, PA (US);
David E Cooper, Palo Alto, CA (US);
David A Zarling, Menlo Park, CA (US);
Michel J Rossi, Cossonay, CH;
Norman A Peppers, Dixon, CA (US);
James Kane, Lawrenceville, NJ (US);
Gregory W Faris, Menlo Park, CA (US);
Mark J Dyer, Richardson, TX (US);
Steve Y Ng, San Francisco, CA (US);
Luke V Schneider, Half Moon Bay, CA (US);
SRI International, Menlo Park, CA (US);
Abstract
The invention provides methods, compositions, and apparatus for performing sensitive detection of analytes, such as biological macromolecules and other analytes, by labeling a probe molecule with an up-converting label. The up-converting label absorbs radiation from an illumination source and emits radiation at one or more higher frequencies, providing enhanced signal-to-noise ratio and the essential elimination of background sample autofluorescence. The methods, compositions, and apparatus are suitable for the sensitive detection of multiple analytes and for various clinical and environmental sampling techniques.