The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2000

Filed:

Oct. 08, 1999
Applicant:
Inventors:

Edward V Thomas, Albuquerque, NM (US);

Robert K Rowe, Corrales, NM (US);

Assignees:

Rio Grande Medical Technologies, Inc., Albuquerque, NM (US);

Sandia Corporaton, Albuquerque, NM (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
250573 ; 25033909 ;
Abstract

A method and apparatus for non-invasively measuring a biological attribute, such as the concentration of an analyte, particularly a blood analyte in tissue such as glucose. The method utilizes spectrographic techniques in conjunction with an improved subject-tailored calibration model. In a calibration phase, calibration model data is modified to reduce or eliminate subject-specific attributes, resulting in a calibration data set modeling within--subject physiological variation, sample location, insertion variations, and instrument variation. In a prediction phase, the prediction process is tailored for each target subject separately using a minimal number of spectral measurements from each subject.


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