The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2000
Filed:
Dec. 07, 1999
Applicant:
Inventors:
Rajashekhar Betageri, Bethel, CT (US);
Jean-Marie Ferland, St. Laurent, CA;
Montse Llinas-Brunet, Dollard-des-Ormeaux, CA;
Neil Moss, Ridgefield, CT (US);
John R Proudfoot, Newtown, CT (US);
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
514426 ; 514427 ; 514506 ; 514553 ; 514708 ; 548557 ; 548560 ; 548561 ; 548565 ; 560 19 ; 560 37 ; 560 55 ; 560 76 ; 562443 ;
Abstract
Disclosed are compositions containing compounds of the formula (I) below wherein A,B,C,G,Q and R are defined herein. The compounds are useful as phosphotyrosine mimics that, when incorporated into an appropriate molecular structure, inhibit the binding of tyrosine kinase-dependent regulatory proteins to their native phosphotyrosine-containing ligands or receptors. Also disclosed are methods for preparing the compounds of the formula (I). ##STR1##