The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2000

Filed:

Jun. 05, 1995
Applicant:
Inventors:

James H Brauker, Lake Villa, IL (US);

Robin Lee Geller, Buffalo Grove, IL (US);

William D Johnston, Kildeer, IL (US);

Steven A Levon, Wauconda, IL (US);

David A Maryanov, Kenosha, WI (US);

Assignee:

Baxter International Inc., Deerfield, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
424 9321 ; 424 932 ; 435375 ; 435325 ; 435366 ; 514 44 ;
Abstract

A method to prevent or treat cancer in a patient comprising: administering a first set of tumor cells; where at least some of the first tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; where the tumor cells are contained in an implantable chamber; the chamber defined by a wall including a porous boundary between the patient's immune cells and the contained cells and pervious to subcellular antigenic material; where the boundary prevents contact between patient immune cells and the contained tumor cells, and where the boundary permits subcellular antigenic materials to exit the chamber; and rendering a second set of tumor cells nontumorigenic; where at least some of the second tumor cells have at least one tumor antigen corresponding to antigen of the patient's tumor cells; administering the second tumor cells to the patient without containing them in a chamber.


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