The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2000

Filed:

Nov. 12, 1998
Applicant:
Inventors:

Robert T Mallet, Arlington, TX (US);

James L Caffrey, Burleson, TX (US);

Maria Isabel Tejero-Taldo, Cedar Hill, TX (US);

Assignee:

My-Tech, Inc., Beverly Hills, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514546 ; 514540 ; 514557 ; 514653 ;
Abstract

A method for treating medical patients suffering from cardiac trauma by co-administering pyruvate with a .beta.-adrenergic agonist. This method for treating cardiac trauma, such as ischemic reperfusion injury and heart failure, augments the inotropic effects of .beta.-adrenergic agents. Typical .beta.-adrenergic agonists are epinephrine, norepinephrine, dobutamine, and isoproterenol. The amount of .beta.-adrenergic agonist necessary to achieve a 50 percent increase of cardiac power is diminished five-fold when co-administered with pyruvate. Since high concentrations of agonists have many detrimental and hazardous side effects in patients, this invention would have important applications in the treatment of patients with cardiac trauma such as ischemia reperfusion injury.


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