The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2000
Filed:
Feb. 18, 1999
Zofia J Chrzan, Sellersville, PA (US);
James J Mencel, Lansdale, PA (US);
David Toledo-Velasquez, Lansdale, PA (US);
Vincent Windisch, Green Lane, PA (US);
Rick G Woodward, Harleysville, PA (US);
Diane C Salazar, deceased, late of Wayne, PA (US);
Narasimha M Vemuri, Phoenixville, PA (US);
Anthony J Gardetto, Oley, PA (US);
Matthew R Powers, Barto, PA (US);
Gregory G Kubiak, Wilmington, DE (US);
Robert C Liu, Walnut Creek, CA (US);
Benoit J Vanasse, Collegeville, PA (US);
James P Sherbine, Voorhees, NJ (US);
Walter Rodriguez, Douglasville, PA (US);
Adam W Sledeski, Collegeville, PA (US);
Aventis Pharmaceuticals Products Inc., Collegeville, PA (US);
Abstract
The invention is directed to a non-hygroscopic stable crystalline form of the antithrombotic compound N-[N-[N-(4-piperdin-4-yl)butanoyl)-N-ethylglycyl]-(L)-aspartyl]-(L)-.beta. -cyclohexyl-alanine amide, to processes for preparing said stable crystalline form, to a pharmaceutical composition thereof, and intermediates thereof, and the invention is directed also to processes for preparing a compound of the formula ##STR1## wherein: A, B, Z, E.sup.1, E.sup.2, G, R, m, n, and p are as defined herein.