The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2000
Filed:
Oct. 18, 1996
Applicant:
Inventors:
Joseph L Kim, Natick, MA (US);
Kurt A Morgenstern, Derry, NH (US);
Chao Lin, Cambridge, MA (US);
Ted Fox, Maynard, MA (US);
John A Thomson, Belmont, MA (US);
Assignee:
Vertex Pharmaceuticals, Incorporated, Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
514-2 ; 514 12 ; 514 13 ; 530324 ; 530325 ; 530326 ; 530350 ; 4241841 ; 4241851 ; 4241891 ; 4242251 ;
Abstract
The present invention relates to compositions and crystals of a hepatitis C virus protease in complex with its viral cofactor. This invention also relates to methods of using the structure coordinates of hepatitis C virus protease in complex with a synthetic NS4A to solve the structure of similar or homologous proteins or protein complexes.