The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2000
Filed:
Aug. 31, 1998
Applicant:
Inventors:
Frank Seela, Osnabruck, DE;
Horst Thomas, Hasbergen, DE;
Assignee:
Aventis Pharma Deutschland GmbH, Frankfurt am Main, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C07H / ; C07H / ; C12Q / ;
U.S. Cl.
CPC ...
536 221 ; 536 231 ; 536 241 ; 536 243 ; 536 253 ; 536 256 ; 536 245 ; 536 271 ; 536 2711 ; 536 2713 ; 435-6 ; 435 911 ; 435 912 ; 514 44 ;
Abstract
Modified oligonucleotides which possess at least one substituted 7-deazapurine base form more stable hybridization complexes with nucleic acids than unsubstituted analogs. They are useful as inhibitors of gene expression, as probes for detecting nucleic acids, as aids in molecular biology and as pharmaceuticals or diagnostic agents. Processes for preparing them are provided.