The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2000
Filed:
Jul. 30, 1998
Applicant:
Inventors:
Robert J Powell, Baltimore, MD (US);
George K Lewis, Baltimore, MD (US);
David M Hone, Ellicott City, MD (US);
Assignee:
University of Maryland at Baltimore, Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; A01N / ; A61K / ;
U.S. Cl.
CPC ...
435455 ; 435455 ; 435472 ; 435480 ; 435 691 ; 4353201 ; 514 44 ; 4241841 ; 424 931 ; 424 9321 ; 424 934 ;
Abstract
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.