The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2000
Filed:
Feb. 16, 1999
Applicant:
Inventors:
Majed M Hamawy, Madison, WI (US);
Stuart J Knechtle, Fitchburg, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ;
U.S. Cl.
CPC ...
435-724 ; 435-6 ;
Abstract
Disclosed herein are methods for monitoring the immunological status of transplant recipients. Fibroblast cells derived from transplanted organs are used in proliferation assays with lymphocytes taken from the recipient after transplantation. The comparison of assay results in the presence of, and in the absence of (or in the presence of reduced levels of) a cytokine growth factor such as interleukin-2, is used to determine whether the organ is being rejected. Also disclosed are kits for practicing these methods.