The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2000

Filed:

Mar. 31, 1998
Applicant:
Inventors:

Friedrich Srienc, Lake Elmo, MN (US);

John K Jackson, Plymouth, MN (US);

David A Somers, Roseville, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01H / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
800298 ; 435 691 ; 4352523 ; 4352542 ; 4353201 ; 435440 ; 435468 ; 435471 ; 536 232 ; 536 237 ; 800278 ;
Abstract

A genetically engineered Pseudomonas oleovorans phaC1 polyhydroxyalkanoate (PHA) polymerase having tailored substrate specificity is provided. The modified PHA polymerase is preferably a 'bispecific' PHA polymerase capable of copolymerizing a short chain length monomer and a medium chain length monomer is provided. Methods for making the modified PHA polymerase and for making nucleic acids encoding the modified PHA polymerase are also disclosed, as are methods of producing PHA using the modified PHA polymerase. The invention further includes methods to assay for altered substrate specificity.


Find Patent Forward Citations

Loading…