The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2000

Filed:

Oct. 16, 1998
Applicant:
Inventors:

Teresa M Bendele, Brunswick, OH (US);

Linda A Harrison, Huron, OH (US);

David J Howard, Oberlin, OH (US);

Lori K Knotts, Medina, OH (US);

Michael L Malek, North Olmsted, OH (US);

Todd A Veverka, Bay Village, OH (US);

Assignee:

Bayer Corporation, Tarrytown, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; B03C / ; B01D / ; C12M / ;
U.S. Cl.
CPC ...
436526 ; 436 47 ; 436807 ; 436809 ; 209214 ; 210222 ; 210695 ; 4352871 ; 4352872 ; 4352873 ; 422 65 ; 422 681 ; 422101 ; 422102 ;
Abstract

Method and apparatus for enabling resuspension wash and magnetic localization of sample components bound to particles with magnetic properties in reaction vessels during separation and wash for enhanced chemiluminescent signal generation in biomedical assays. The assays involve moving reaction vessels past magnets that partially localize the particles prior to passing a reduced strength magnet where washing occurs, with or without resuspension, after separating out the unbound particles and liquid. The band of particles is subsequently resuspended in acid for chemiluminescent purposes. A variety of magnet configurations are employed to realize the reduced strength magnet. Reduced strength magnets adjacent the full width magnets prevent the band of magnetic particles from becoming split. The localized particles enable more efficient resuspension by reagent.


Find Patent Forward Citations

Loading…