The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2000
Filed:
Apr. 15, 1998
Applicant:
Inventors:
Wayne A Marasco, Wellesley, MA (US);
Jennifer Richardson, Boston, MA (US);
Maria Cristina Parolin, Padua, IT;
Joseph G Sodroski, Medford, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
435 691 ; 4241991 ; 4242081 ; 435 693 ; 435 9142 ; 4351723 ;
Abstract
The present invention is related to vectors and methods for increasing the expression of a desired gene product. Preferably this invention is used with genes expressing proteins that are not well tolerated by mammalian cells or where high levels of expression are necessary. In certain preferred embodiments it can be used as part of a multi-tiered expression system and with methods of intracellularly targeting a molecule.