The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2000
Filed:
Feb. 01, 1999
Applicant:
Inventors:
Charles G Caldwell, Scotch Plains, NJ (US);
Malcolm Maccoss, Freehold, NJ (US);
Paul E Finke, Milltown, NJ (US);
Sander G Mills, Scotch Plains, NJ (US);
Bryan Oates, Wayne, NJ (US);
Shankaran Kothandaraman, Kendall Park, NJ (US);
Dooseop Kim, Westfield, NJ (US);
Liping Wang, Plainsboro, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514326 ; 514322 ; 514329 ; 546199 ; 546210 ; 546212 ; 546213 ; 546214 ; 546224 ;
Abstract
The present invention is directed to cyclic amines of the formula I: ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.