The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2000
Filed:
Oct. 08, 1998
Applicant:
Inventors:
Lovji D Cama, Tenafly, NJ (US);
Robert R Wilkening, Maplewood, NJ (US);
Ronald W Ratcliffe, Matawan, NJ (US);
Kenneth J Wildonger, Bridgewater, NJ (US);
Wanying Sun, Edison, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
51421009 ; 51425402 ; 540302 ; 544368 ;
Abstract
Compounds of formula I are disclosed. ##STR1## as well as pharmaceutically acceptable salts thereof. The naphthosultam is substituted with various substituent groups including at least one cationic group -A-Q-L-B. The carbapenems of the invention are effective against susceptible bacterial organisms, including methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS).