The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2000
Filed:
May. 06, 1998
Applicant:
Inventor:
Arnold Glazier, Newton, MA (US);
Assignee:
Drug Innovation & Design, Inc., Waltham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ; C07F / ;
U.S. Cl.
CPC ...
514 47 ; 514 48 ; 514 51 ; 514 52 ; 536 267 ; 536 2671 ; 536 2672 ; 536 2674 ; 536 268 ; 536 269 ; 568-8 ; 568 13 ; 568 14 ;
Abstract
The composition and methods of synthesis of phosphorus prodrugs are described. These methods can be used to convert negatively charged phosphorus bearing drugs into neutrally charged; lipid soluble prodrugs which are able to passively diffuse into cells and into tissues in vivo. Prodrugs for a variety of antiviral and anti-leukemic agents are described.